association between tnf-alpha (-857) gene polymorphism and susceptibility to tuberculosis
نویسندگان
چکیده
منابع مشابه
Association between TNF-Alpha (-857) Gene Polymorphism and Susceptibility to Tuberculosis
BACKGROUND TNF-α as a pro-inflammatory cytokine plays a key role in host defense against tuberculosis (TB). Presence of mutation in TNF-α gene can influence the effectiveness, performance and capability of immune responses against this infection. The Aim of this study was to investigate the frequency of TNF-α alleles and its relationship with susceptibility to TB and TNF-α gene variations. ME...
متن کاملGenetic association between TNF-α −857 C/T polymorphism and ankylosing spondylitis susceptibility: evidence from a meta-analysis
Certain studies have suggested that the tumor necrosis factor-α (TNF-α) -857 C/T polymorphism is associated with risk of ankylosing spondylitis. However, the conclusions remain controversial. Therefore, we performed a meta-analysis to provide a more precise conclusion. Such databases as PubMed, Embase, CBM, CNKI, and Wanfang Data were searched to identify relevant studies up to August 26, 2015....
متن کاملThe Association between TNF-alpha Gene Polymorphisms and Endometriosis in An Iranian Population
Objective Objective: TNF-α is an important cytokine in acute inflammatory response to infective factors. It seems that this response increases in patients with endometriosis due to presence of cytokines such as TNF-α which has been investigated in patients with endometriosis in different populations. This study aimed at examining four polymorphisms; TNF-α -238G/A, -308G/A, -857C/T and -863C/A a...
متن کاملLack of Association Between miRNA-146a rs2910164 and miRNA-499 rs3746444 Gene Polymorphisms and Susceptibility to Pulmonary Tuberculosis
Single-nucleotide polymorphisms (SNPs) in miRNAsmay alter its expression levels or processing and contribute to susceptibility to a wide range of diseases. Our study aimed to evaluate the possible association between miRNA-146a rs2910164 and miRNA-499 rs3746444 polymorphisms and susceptibility to pulmonary tuberculosis (PTB) in a sample of Iranian population. This case- control study was perfor...
متن کاملEvaluation of Relationship between Single-nucleotide Polymorphism in TNF-gene Promoter and Susceptibility to Atherosclerosis in Fatemeh Zahra Hospital
Background: Tumor necrosis factor alpha is a proinflammatory cytokine and as polyvalent initial response of inflammatory cells which facilitated through the creation of coronary atherosclerosis . It also seems that the polymorphism and susceptibility to atherosclerosis is related to TNF-α gene promoter. The purpose of this study was to investigate single nucleotide polymorphis...
متن کاملAssociation between CD127 Gene Polymorphism and Susceptibility to Multiple Sclerosis
Fereshteh Alsahebfosoul1,6*, Rasoul Salehi2, Masoud Etemadifar3,5, Ahmad Zavaran Hosseini4, Mohammad Kazemi2, Mehrdad Farokhi5,6, and Mohadaseh Behjati5 1Immunology Department, Faculty of medicine, Isfahan University of medical sciences, Isfahan, Iran 2Molecular biology and genetics Department, Faculty of medicine, Isfahan University of medical sciences, Isfahan, Iran 3Neurology Department, Fac...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian red crescent medical journalجلد ۱۳، شماره ۴، صفحات ۲۴۳-۲۴۸
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023